Azadirachta Indica (Neem) in Traditional Indian Medicine: Indigenous Knowledge & Scientific Validation

Neem, scientifically known as Azadirachta indica, has been an integral part of human history for millennia, especially in the Indian subcontinent. Its significance in ancient times can be seen in various aspects such as traditional, medicinal and cultural. Neem’s versatility and wide range of usage made it an invaluable resource since ancient time. Its legacy continues to be celebrated in modern times for its numerous benefits. Bark, leaves, and roots contain Antimicrobial, Antifungal, Insecticidal, Antiviral, Anti-Malarial, Antiperiodic, Mosquito Larvicidal, Anti-Inflammatory, Antifertility, Spermicidal, and Hypoglycaemic properties. In modern time the medicinal and healing properties of Azadirachta indica can be interpretate by using the chemical analysis technique i.e. GC-MS. The chemical and biological analysis of Azadirachta indica (Neem) discovered the existence of many bioactive substances in various plant parts, including limonoids (Azadirachtin, nimbin and nimbidin), flavonoids (Quercetin, catechin), phenolic compound (Gallotannins and Ellagic Acid), alkaloids and sulfur compounds (Margolone and Margolonone). These bioactive compounds are responsible for bioactivity of various part of Azadirachta indica . Hence, this article is aimed highlighting  the therapeutical potential of Neem plant, and bringing together traditional practices and modern sciences with a scientific validation through GC-MS Analysis.